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Drug Class: Commonly Known As: Category:
Zopiclone Imovane, Zimovane Adult

Zopiclone - Side Effects, Precautions, and Contraindications

What side effects can Zopiclone cause?

Potential side effects

All medicines may cause side effects. However, many people do not experience them.

Most of the side effects listed here will improve with time. Speak with your doctor or pharmacist if they persist, become bothersome or worsen.


Side effectsWhat to do about it
Bad breath, dry mouth, bitter tasteSip water regularly. Sucking on sugar-free sweets or ice chips may help to alleviate symptoms of dry mouth. Avoid caffeine as it may worsen dry mouth.

Do not drive or operate any machinery. You may still feel sleepy the day after you take this medication. Avoid doing tasks that call for you to be alert until you feel fully awake.

DizzinessGet up slowly from a lying or sitting position


Serious side effects

Seek medical help as soon as possible if you have any of the following signs or symptoms.

  • Allergy such as rashes, swelling of lips/face/throat, difficulty breathing
  • Feeling excitable, over-talkative, disinhibited and having intrusive thoughts
  • Altered mood including new or worsening thoughts of self-harm.


Take note that the side effects listed here are not exhaustive. Do seek medical attention if you have other symptoms that you think may be related to this medicine.

Before taking Zopiclone, what precautions must I follow?

​What do I need to tell my doctor before I take this medicine?

  • Drug allergies.
  • Pre-existing medical conditions such as lung disease, liver disease, myasthenia gravis and sleep apnoea (temporary stopping of breathing during sleep).
  • Whether you are taking any other medicines, supplements or traditional medicines. Some of them may affect how this medicine works.
  • For women: Tell your doctor if you are pregnant or breast-feeding or have plans to become pregnant. If you are pregnant and/or breastfeeding, your doctor would have discussed the potential benefits and side-effects of starting/continuing this medicine with you but should you have further questions or concerns, do consult your doctor.

What food or medicine must I avoid when I take Zopiclone?

​This medicine may interact with a number of other medicines. This is particularly the case for medicines which may alter your mood, certain painkillers and other medicines which may cause drowsiness. Inform your doctor if you are taking or intend to take other medicines or supplements.

Avoid alcohol while taking this medicine.

Zopiclone - Additional Information

​What are the things I need to know or look out for while on this medicine?

  • Avoid driving or any other activities that requires concentration until you see how this medicine affects you.
  • Inform your other healthcare professionals that you are on this medicine as well.
  • Discuss with your doctor or pharmacist before you take any other medicines or natural products.
  • Taking this medicine along with opioid drugs such as codeine and morphine may lead to side effects. Inform your healthcare provider if you are taking any painkillers or cough preparations.
  • Ensure that you have at least 7-8 hours of sleep if you take this medicine. It is recommended to wait at least 12 hours before engaging in activities that requires concentration such as driving.
  • Do not share your medicines with others.
  • Consult your doctor or pharmacist if you have any questions about your medicine.

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