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Research Publications

2017 (Jan - Jun)

  • Ma D, Ng SH, Zeng L, Zhao Y, Tan EK.Generation of a human induced pluripotent stem cell (iPSC) line carrying the Parkinson's disease linked LRRK2 variant S1647T.Stem Cell Res.2017 Jan;18:54-56. doi: 10.1016/j.scr.2016.12.010. Epub 2016 Dec 9. IF 3.494
  • Ma D, Ng EY, Zeng L, Lim CY, Zhao Y, Tan EK.Development of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient carrying the N551K variant in LRRK2 gene.Stem Cell Res. 2017 Jan;18:51-53. doi: 10.1016/j.scr.2016.12.013. Epub 2016 Dec 8. IF 3.494
  • Ma D, Tio M, Ng SH, Li Zeng, Lim CY, Zhao Y, Tan EK.Derivation of human induced pluripotent stem cell (iPSC) line with LRRK2 gene R1398H variant in Parkinson's disease.Stem Cell Res.2017 Jan;18:48-50. doi: 10.1016/j.scr.2016.12.014. Epub 2016 Dec 9. IF 3.494
  • Ma D, Zhou W, Ng EY, Zeng L, Zhao Y, Tan EK.Reprogramming of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient with a R1628P variant in the LRRK2 gene.Stem Cell Res. 2017 Jan;18:45-47. doi: 10.1016/j.scr.2016.12.011. Epub 2016 Dec 10. IF 3.494
  • Alomar S, King NK, Tam J, Bari AA, Hamani C, Lozano AM.Speech and language adverse effects after thalamotomy and deep brain stimulation in patients with movement disorders: A meta-analysis.Mov Disord. 2017 Jan;32(1):53-63. doi: 10.1002/mds.26924. Review. IF 7.072
  • Hong Cheng SK, Tang YL, Prashanth RJ, Chuah KL.Extradural Brain Mass in a 64-Year-Old Man.Brain Pathol.2017 Jan;27(1):115-116. doi: 10.1111/bpa.12465. IF 5.272
  • Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, et al.Genome-wide association study of Parkinson's disease in East Asians.Hum Mol Genet.2017 Jan 1;26(1):226-232. doi: 10.1093/hmg/ddw379. IF 5.34
  • Sinha RA, Singh BK, Zhou J, Xie S, Farah BL, Lesmana R, Ohba K, Tripathi M, Ghosh S, Hollenberg AN, Yen PM.Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells.Autophagy.2017 Jan 2;13(1):169-186. doi: 10.1080/15548627.2016.1235123. Epub 2016 Nov 15. IF 8.593
  • Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, et al..Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study.Neurobiol Aging.2017 Jan;49:217.e1-217.e4. doi: 10.1016/j.neurobiolaging.2016.09.022. Epub 2016 Oct 6. IF 5.117
  • Thien A, See AA, Ang SY, Primalani NK, Lim MJ, Ng YP, King NK.Prevalence of Asymptomatic Unruptured Intracranial Aneurysms in a Southeast Asian Population.World Neurosurg.2017 Jan;97:326-332. doi: 10.1016/j.wneu.2016.09.118. Epub 2016 Oct 12. IF 2.592
  • Ang SY, Ng VW, Kumar SD, Low SY.Cryptococcosis mimicking lung carcinoma with brain metastases in an immunocompetent patient.J Clin Neurosci.2017 Jan;35:73-75. doi: 10.1016/j.jocn.2016.09.016. Epub 2016 Oct 18. IF 1.557
  • Ho NF, Iglesias JE, Sum MY, Kuswanto CN, Sitoh YY, De Souza J, Hong Z, Fischl B, Roffman JL, Zhou J, Sim K, Holt DJ.Progression from selective to general involvement of hippocampal subfields in schizophrenia.Mol Psychiatry.2017 Jan;22(1):142-152. doi: 10.1038/mp.2016.4. Epub 2016 Feb 23 IF13.204
  • Chia PS, Hameed S, Yong KP, Chan LL, Ting SK.Hyperfamiliarity in Amnestic and Vascular Mild Cognitive Impairment. Canadian Journal of Neurological Sciences. Volume 44, Issue 1 January 2017, pp. 17-23. DOI: 10.1017/cjn.2016.403 IF 0.952
  • Tan K, Wijaya L, Chiew HJ, Sitoh YY, Shafi H, Chen RC, Goh CK, Lim CC.Diffusion-weighted MRI abnormalities in an outbreak of Streptococcus agalactiae Serotype III, multilocus sequence type 283 meningitis.J Magn Reson Imaging.2017 Feb;45(2):507-514. doi: 10.1002/jmri.25373. Epub 2016 Jul 29. IF 3.083
  • Liew NC, Alemany GV, Angchaisuksiri P, Bang SM, Choi G, DE Silva DA, Hong JM, Lee L, Li YJ, Rajamoney GN, Suviraj J, Tan TC, Tse E, Teo LT, Visperas J, Wong RS, Lee LH.Asian venous thromboembolism guidelines: updated recommendations for the prevention of venous thromboembolism.Int Angiol.2017 Feb;36(1):1-20. doi: 10.23736/S0392-9590.16.03765-2. Epub 2016 Sep 8. IF 1.37
  • Neo S, Lee KE.Collet-Sicard syndrome: a rare but important presentation of internal jugular vein thrombosis.Pract Neurol.2017 Jan;17(1):63-65. doi: 10.1136/practneurol-2015-001268. Epub 2016 Nov 3. IF 0.93
  • Zhu W, Mitsuhashi S, Yonekawa T, Noguchi S, Huei JC, Nalini A, Preethish-Kumar V, Yamamoto M, Murakata K, Mori-Yoshimura M, Kamada S, Yahikozawa H, Karasawa M, Kimura S, Yamashita F, Nishino I.Missing genetic variations in GNE myopathy: rearrangement hotspots encompassing 5'UTR and founder allele.J Hum Genet.2017 Feb;62(2):159-166. doi: 10.1038/jhg.2016.134. Epub 2016 Nov 10. IF 2.471
  • Thien A, Rao JP, Ng WH, King NK..The Fluoropen: a simple low-cost device to detect intraoperative fluorescein fluorescence in stereotactic needle biopsy of brain tumors.Acta Neurochir (Wien).2017 Feb;159(2):371-375. doi: 10.1007/s00701-016-3041-8. Epub 2016 Dec 10. IF 1.881
  • Foo H, Mak E, Yong TT, Wen MC, Chander RJ, Au WL, Sitoh YY, Tan LC, Kandiah N.Progression of subcortical atrophy in mild Parkinson's disease and its impact on cognition.Eur J Neurol.2017 Feb;24(2):341-348. doi: 10.1111/ene.13205. Epub 2016 Dec 10. IF 3.988
  • Adriani G, Ma D, Pavesi A, Kamm RD, Goh EL.A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood-brain barrier.Lab Chip.2017 Jan 31;17(3):448-459. doi: 10.1039/c6lc00638h. IF 6.045
  • Koelman DL, Benkeser DC, Xu Y, Neo SX, Tan K, Katsuno M, Sobue G, Natsume J, Chahin S, Mar SS, Venkatesan A, Chitnis T, Hoganson GM, Yeshokumar AK, Barreras P, Majmudar B, Carone M, Mateen FJ.Acute disseminated encephalomyelitis in China, Singapore and Japan: a comparison with the USA.Eur J Neurol.2017 Feb;24(2):391-396. doi: 10.1111/ene.13220. Epub 2016 Dec 23. IF 3.988
  • Angamuthu N, Queck KK, Menon S, Ho SS, Ang E, De Silva DA.Surveys of Stroke Patients and Their Next of Kin on Their Opinions towards Decision-Making and Consent for Stroke Thrombolysis.Ann Acad Med Singapore.2017 Feb;46(2):50-63. IF 0.617
  • Sachdev PS, Lo JW, Crawford JD, Mellon L, Hickey A, Williams D, Bordet R, Mendyk AM, Gelé P, Deplanque D, Bae HJ, Lim JS, Brodtmann A, Werden E, Cumming T, Köhler S, Verhey FR, Dong YH, Tan HH, Chen C, Xin X, Kalaria RN, et al.STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease.Alzheimers Dement (Amst).2016 Nov 18;7:11-23. doi: 10.1016/j.dadm.2016.10.006. eCollection 2017. IF 11.619
  • Lin X, Yu WY, Liauw L, Chander RJ, Soon WE, Lee HY, Tan K. Clinicoradiologic features distinguish tumefactive multiple sclerosis from CNS neoplasms. Neurol Clin Pract 2017 Feb;7(1):53-64. IF 0.49
  • Qiu L, Upadhyaya T, See AA, Ng YP, Kon Kam King N.Incidence of Recurrent Intracerebral Hemorrhages in a Multiethnic South Asian Population.J Stroke Cerebrovasc Dis.2017 Mar;26(3):666-672. doi: 10.1016/j.jstrokecerebrovasdis.2016.10.044. Epub 2016 Nov 29. IF 1.517
  • Lin X, Lee M, Buck O, Woo KM, Zhang Z, Hatzoglou V, Omuro A, Arevalo-Perez J, Thomas AA, Huse J, Peck K, Holodny AI, Young RJ.Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced-MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma.AJNR Am J Neuroradiol.2017 Mar;38(3):485-491. doi: 10.3174/ajnr.A5023. Epub 2016 Dec 8. IF 3.55
  • Chua FHZ, Thien A, Ng LP, Seow WT, Low DCY, Chang KTE, Lian DWQ, Loh E, Low SYY.Post-operative diffusion weighted imaging as a predictor of posterior fossa syndrome permanence in paediatric medulloblastoma.Childs Nerv Syst.2017 Mar;33(3):457-465. doi: 10.1007/s00381-017-3356-7. Epub 2017 Feb 11. IF 1.081
  • Liew ZH, Lo YL.Intravenous Immunoglobulin in Treatment of Hereditary Neuropathy With Liability to Pressure Palsy.J Clin Neuromuscul Dis.2017 Mar;18(3):160-161. doi: 10.1097/CND.0000000000000153. No abstract available. IF 0.55
  • Saini M, Varghese NM, Su Wai KH, Loh NK.Rapidly progressive dementia with myoclonus: Not Creutzfeldt-Jakob disease.Neurol India.2017 Mar-Apr;65(2):426-427. doi: 10.4103/neuroindia.NI_57_16. No abstract available. IF 1.758
  • Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P.Monoamine oxidase B inhibitor, selegiline, reduces (18)F-THK5351 uptake in the human brain..Alzheimers Res Ther.2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y IF 6.196
  • Ang K, Maddocks M, Xu H, Higginson IJ.The Effectiveness of Singing or Playing a Wind Instrument in Improving Respiratory Function in Patients with Long-Term Neurological Conditions: A Systematic Review.J Music Ther.2017 Mar 1;54(1):108-131. doi: 10.1093/jmt/thx001. Review. IF 1
  • Xu Z, Zhang J, Ng SY, Chai JY, Tan LC..Adult Onset Sporadic Cerebellar Ataxia in Singapore: Diagnostic Outcomes of Paraneoplastic Antibody Testing and Early Clinical Features of Paraneoplastic Cerebellar Degeneration.Ann Acad Med Singapore.2017 Mar;46(3):118-120. No abstract available. IF 0.617
  • Kandiah N, Pai MC, Senanarong V, Looi I, Ampil E, Park KW, Karanam AK, Christopher S.Rivastigmine: the advantages of dual inhibition of acetylcholinesterase and butyrylcholinesterase and its role in subcortical vascular dementia and Parkinson's disease dementia.Clin Interv Aging.2017 Apr 18;12:697-707. doi: 10.2147/CIA.S129145. eCollection 2017. Review IF 2.581
  • Laskowitz DT, Wang H, Chen T, Lubkin DT, Cantillana V, Tu TM, Kernagis D, Zhou G, Macy G, Kolls BJ, Dawson HN.Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model.Sci Rep.2017 Apr 21;7:46461. doi: 10.1038/srep46461. IF 4.259
  • Narayanan G, Sheila M, Chai J, Stanton LW.Generation of sibling-matched induced pluripotent stem cell lines from spinal and bulbar muscular atrophy patients.Stem Cell Res.2017 Apr;20:30-33. doi: 10.1016/j.scr.2017.02.005. Epub 2017 Feb 16. IF 3.494
  • Tu TM, Kolls BJ, Soderblom EJ, Cantillana V, Ferrell PD, Moseley MA, Wang H, Dawson HN, Laskowitz DT.Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke.Ann Clin Transl Neurol.2017 Mar 9;4(4):246-265. doi: 10.1002/acn3.399. eCollection 2017 Apr. IF 3.901
  • Xiao B, Deng X, Ng EY, Tio M, Prakash KM, Au WL, Tan L, Zhao Y, Tan EK.GWAS-linked PPARGC1A variant in Asian patients with essential tremor.Brain.2017 Apr 1;140(4):e24. doi: 10.1093/brain/awx027. No abstract available. IF 10.292
  • Chua FHZ, Low DCY, Lian DWQ, Tew SW, Low SYY.Anomalous intracranial germinoma with unilateral cerebral peduncle swelling.Childs Nerv Syst.2017 Apr;33(4):563-565. doi: 10.1007/s00381-017-3355-8. Epub 2017 Mar 10. No abstract available. IF 1.081
  • Husain N, Yuan Q, Yen YC, Pletnikova O, Sally DQ, Worley P, Bichler Z, Shawn Je H..TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation..Aging Cell.2017 Apr;16(2):281-292. doi: 10.1111/acel.12551. Epub 2016 Dec 20.
  • Venketasubramanian N, Yin A, Lee LB, De Silva DA.Two decades of nation-wide community-based stroke support - The Singapore National Stroke Association.Int J Stroke.2017 Apr;12(3):297-301. doi: 10.1177/1747493016676620. Epub 2016 Oct 24 IF 3.314
  • Ho IAW, Shim WSN.Contribution of the Microenvironmental Niche to Glioblastoma Heterogeneity.Biomed Res Int.2017;2017:9634172. doi: 10.1155/2017/9634172. Epub 2017 May 28. Review. IF 2.476
  • Li G, Wang J, Liao P, Bartels P, Zhang H, Yu D, Liang MC, Poh KK, Yu CY, Jiang F, Yong TF, Wong YP, Hu Z, Huang H, Zhang G, Galupo MJ, Bian JS, Ponniah S, Trasti SL, See K, Foo R, Hoppe UC, et al..Exclusion of alternative exon 33 of Ca(V)1.2 calcium channels in heart is proarrhythmogenic.Proc Natl Acad Sci U S A.2017 May 23;114(21):E4288-E4295. doi: 10.1073/pnas.1617205114. Epub 2017 May 10. IF 9.661
  • Tan YJ, Ng ASL, Vipin A, Lim JKW, Chander RJ, Ji F, Qiu Y, Ting SKS, Hameed S, Lee TS, Zeng L, Kandiah N, Zhou J.Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic Mild Cognitive Impairment.J Alzheimers Dis.2017;58(2):413-423. doi: 10.3233/JAD-161277 IF 3.731
  • Lo YL, Najjar RP, Teo KY, Tow SL, Loo JL, Milea D.A reappraisal of diagnostic tests for myasthenia gravis in a large Asian cohort.J Neurol Sci.2017 May 15;376:153-158. doi: 10.1016/j.jns.2017.03.016. Epub 2017 Mar 14. IF 2.295
  • Xu Z, Lim TCC, Au WL, Tan LCS.Progressive Supranuclear Gaze Palsy with Predominant Cerebellar Ataxia: A Case Series with Videos.J Mov Disord.2017 May;10(2):87-91. doi: 10.14802/jmd.16059. Epub 2017 Apr 18. IF 6.01
  • Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedet AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P, Gauthier S; Alzheimer's Disease Neuroimaging Initiative..Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease..Neurology.2017 May 9;88(19):1814-1821. doi: 10.1212/WNL.0000000000003916. Epub 2017 Apr 12. IF 7.592
  • Xu Z, Prasad K, Yeo T.Progressive Encephalomyelitis with Rigidity and Myoclonus in an Intellectually Disabled Patient Mimicking Neuroleptic Malignant Syndrome.J Mov Disord.2017 May;10(2):99-101. doi: 10.14802/jmd.16058. Epub 2017 Mar 24. IF 6.01
  • Muhlhofer W, Tan YL, Mueller SG, Knowlton R.MRI-negative temporal lobe epilepsy-What do we know?.Epilepsia.2017 May;58(5):727-742. doi: 10.1111/epi.13699. Epub 2017 Mar 7. Review. IF 5.295
  • Deng X, Hao Y, Xiao B, Tan EK, Lo YL.Risk factors for respiratory failure of motor neuron disease in a multiracial Asian population.J Clin Neurosci.2017 May;39:137-141. doi: 10.1016/j.jocn.2016.12.018. Epub 2017 Jan 12. IF 1.557
  • King NKK, Krishna V, Basha D, Elias G, Sammartino F, Hodaie M, Lozano AM, Hutchison WD.Microelectrode recording findings within the tractography-defined ventral intermediate nucleus.J Neurosurg.2017 May;126(5):1669-1675. doi: 10.3171/2016.3.JNS151992. Epub 2016 Jul 22. IF 4.059
  • Tu TM, Phua SS, Acharyya S, Ng WM, Oh DC.Predicting Pneumonia in Acute Ischaemic Stroke: Comparison of Five Prediction Scoring Models.Ann Acad Med Singapore.2017 Jun;46(6):237-244. IF 0.617
  • Koh YH.A rare case of Ludwig's angina after viper bite.BMJ Case Rep.2017 Jun 9;2017. pii: bcr-2016-218427. doi: 10.1136/bcr-2016-218427. No abstract available.
  • Ng ASL, Tan EK.Linking statins and lipids in Parkinson's disease.Mov Disord.2017 Jun;32(6):807-809. doi: 10.1002/mds.27053. Epub 2017 May 27. No abstract available. IF 7.072
  • Lim GG, Lim KL.Parkin-independent mitophagy-FKBP8 takes the stage.EMBO Rep.2017 Jun;18(6):864-865. doi: 10.15252/embr.201744313. Epub 2017 May 17. IF 8.568
  • Shi H.Risk Factors for Aneurysm Recurrence.Radiology.2017 Jun;283(3):919-920. doi: 10.1148/radiol.2017162628. No abstract available. IF 7.296
  • Ong M, Foo H, Chander RJ, Wen MC, Au WL, Sitoh YY, Tan L, Kandiah N.Influence of diabetes mellitus on longitudinal atrophy and cognition in Parkinson's disease.J Neurol Sci.2017 Jun 15;377:122-126. doi: 10.1016/j.jns.2017.04.010. Epub 2017 Apr 11. IF 2.295
  • Chan SL, Tan EK.Targeting LRRK2 in Parkinson's disease: an update on recent developments.Expert Opin Ther Targets.2017 Jun;21(6):601-610. doi: 10.1080/14728222.2017.1323881. Epub 2017 May 15. Review. IF 4.873
  • Low SYY, Lian DWQ, Tang PH, Loh E, Seow WT, Low DCY.Concurrent paediatric medulloblastoma and Chiari I malformation with syringomyelia.Childs Nerv Syst.2017 Jun;33(6):881-883. doi: 10.1007/s00381-017-3413-2. Epub 2017 Apr 21. No abstract available. IF 1.081
  • Ho NF, Li Z, Ji F, Wang M, Kuswanto CN, Sum MY, Tng HY, Sitoh YY, Sim K, Zhou J.Hemispheric lateralization abnormalities of the white matter microstructure in patients with schizophrenia and bipolar disorder.J Psychiatry Neurosci.2017 Jun;42(4):242-251 IF 5.165
  • uptill JT, Raja SM, Boakye-Agyeman F, Noveck R, Ramey S, Tu TM, Laskowitz DT.Phase 1 Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, and Pharmacokinetics of a Single Escalating Dose and Repeated Doses of CN-105 in Healthy Adult Subjects.J Clin Pharmacol.2017 Jun;57(6):770-776. doi: 10.1002/jcph.853. Epub 2016 Dec 19. IF 2.812
  • So RQ, Krishna V, King NKK, Yang H, Zhang Z, Sammartino F, Lozano AM, Wennberg RA, Guan C.Prediction and detection of seizures from simultaneous thalamic and scalp electroencephalography recordings.J Neurosurg.2017 Jun;126(6):2036-2044. doi: 10.3171/2016.7.JNS161282. Epub 2016 Oct 7. IF 4.059