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Bicalutamide

Drug Class: Commonly Known As: Category:
Antiandrogen Casodex® Cancer-related

Bicalutamide - What is it for

​Bicalutamide is a medicine that is used to treat prostate cancer. It works by blocking the effect of a male sex hormone - testosterone.

Bicalutamide - Side Effects, Precautions, and Contraindications

What side effects can Bicalutamide cause?

  • Nausea and vomiting may occur and should subside as treatment continues.
  • If nausea occurs, eat and drink in smaller portions, but more frequently.
  • Hot flushes can sometimes occur when you first start taking Bicalutamide.
  • If this occurs, take the tablet at bedtime. If night sweat interferes with sleep, try taking the tablet in the morning.
  • Decreased sexual ability or desire may occur. This will return to normal when the treatment is stopped.
  • Some tiredness and weakness
  • Mild swelling in your ankles, legs or feet
  • Constipation or diarrhea may occur.
  • ​Exercise if you can, and drink sufficient amount of fluids.

Inform your doctor if any of the following occurs:

  • Skin rashes, hives or itching
  • Shortness of breath or difficulty in breathing
  • Confusion or dizziness
  • Yellowing of the skin or eyes or dark tea-coloured urine

Before taking Bicalutamide, what precautions must I follow?

  • Inform your doctor or pharmacist of any other medical conditions you have as well as any other medicines or supplements you are taking e.g. warfarin.
  • Use effective birth control methods during treatment with Bicalutamide and for 130 days after stopping treatment.

What food or medicine must I avoid when I take Bicalutamide?

Bicalutamide - Dosage and How to Use

How should Bicalutamide be used?

​It is a tablet, to be taken by mouth at the same time every day. It can be taken with food or on an empty stomach, with a glass of water or juice.

What should I do if I miss a dose?

If you miss a dose of Bicalutamide, take it as soon as you can if it is within 12 hours of the missed dose. If more than 12 hours have passed, skip the missed dose and go back to your usual dosing time. Do not double dose.

What should I do if I overdose?

​If you overdose on this medicine, inform your doctor immediately.

Bicalutamide - Handling and Storage

How should I handle Bicalutamide safely?

How should I store Bicalutamide?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Bicalutamide safely?

Bicalutamide - Additional Information

  • Updated on Monday, March 19, 2018
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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