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Clinical Trials & Research

Dementia, Parkinson disease and many other neurological conditions currently have no cure. Our researchers are working hard to change that but they need your help to succeed.

By taking part in clinical trials and research projects, you can help us better understand the brain, improve treatments for disabling conditions and help your loved ones enjoy better brain health in the future.

We are no longer recruiting participants for the following research studies as they have ended:


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Brain & Body Changes in Early Stage Dementia

NNI researchers are studying how changes in brain structure, proteins in blood and spinal fluid impact memory and thinking in young and older patients.

What the study involves:
  • 1 to 3 visits per year (depending on tests conducted) for 5 years
  • Tests include (based on pre specified criteria)
    • PET scans
    • MRI scans
    • Blood tests
    • Spinal tap
    • Eye examination
    • Neuropsychological assessments
    • Reimbursement is provided

Click for details


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Ginkgo biloba Extract and Dementia

We are studying if a dried extract (EGb 761) from the leaves of the Gingko biloba plant can stop mild forgetfulness (mild cognitive impairment) from progressing
to dementia in people with damaged blood vessels in the brain (cerebrovascular disease).

What the study involves:
  • 3 to 4 visits to NNI during the clinical trial within 1 year
  • One time blood test
  • Participants may be given the EGb 761 treatment during the trial
  • Transport reimbursement is provided

Click for details


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Spinal Ultrasound Scans

This study is collecting ultrasound images of spines to develop an artificial intelligence (AI) powered system for lumbar puncture.

What the study involves:
  • You will be asked to lie on your side on an examination bed
  • An ultrasound scan will be done on your lower (lumbar) spine
  • The scan will take less than 30 minutes
  • No invasive procedures or needles will be used
  • One visit only - no follow-up visit required
  • Transport reimbursement is provided

Click for details