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Assoc Prof Adeline Ng

Assoc Prof Adeline Ng

MBChB (Edinburgh), MRCP (United Kingdom)

Research Interest:
  • ​Neurodegenerative diseases
  • Cognitive neurology

Clinical Appointments

  • Deputy Head & Director, Research SingHealth Duke-NUS Centre of Memory and Cognitive Disorders
  • Director, Special Projects, Office of Academic Affairs National Neuroscience InstituteNational Neuroscience Institute
  • Senior Consultant Department of Neurology National Neuroscience InstituteNational Neuroscience Institute


Assoc Prof Adeline Ng is a Senior Consultant Neurologist and Director, Special Projects, Office of Academic Affairs at the National Neuroscience Institute (NNI@TTSH). She has a keen interest in cognitive and behavioural neurology, and completed a one-year fellowship at the Memory and Aging Centre, University of California, San Francisco, focusing on Young-Onset Dementias (YODs). Her main interests in clinical research are in neurodegenerative diseases and cognitive neurology, with a focus on genetics and biomarkers.

Professional Appointments and Committee Memberships

  • Senior Consultant, Department of Neurology, National Neuroscience Institute
  • Director, Special Projects, Office of Academic Affairs, National Neuroscience Institute
  • Head, Department of Psychology, National Neuroscience Institute
  • Programme Director, Dementia and Cognitive Neuroscience, National Neuroscience Institute
  • Clinical Associate Professor, Neuroscience ACP, Duke-NUS


  • MRCP (United Kingdom), 2007
  • MBChB (Edinburgh), 2003


  • National Medical Research Council (NMRC) Awards, Clinician Scientist Award – Investigator, 2022
  • SingHealth Excellence Awards, Distinguished Young Researcher Award, 2021
  • ​SingHealth Residency (RiSE) Outstanding Faculty Award, 2016
  • SingHealth Best Medical Officer Award, 2008

Research Studies


  • ​Ng ASL, E Ng, YJ Tan, N Kandiah, J Zhou, S Hameed, S Ting, EK Tan. Case-control analysis of LRRK2 protective variants in Alzheimer’s disease. Neurobiol Aging. 2017
  • Ng ASL, Tan EK. Intermediate C9orf72 alleles in neurological disorders: does size really matter? J Med Genet. 2017 Jul 8.
  • Ng ASL, Tan EK. Linking statins and lipids in Parkinson’s disease. Mov Disord. 2017 Jun;32(6):807-80
  • Tan YJ*, Ng ASL*, Vipin A, Lim JKW, Chander RJ, Ji F, Qiu Y, Ting SKS, Hameed S, Lee TS, Zeng L, Kandiah N, Zhou J. Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic Mild Cognitive Impairment. J Alzheimers Dis. 2017;58(2):413-423 *joint first author
  • Ng ASL. Genetics of frontotemporal dementia in Asia: Advancing knowledge through collaboration. Neurology 2015; 85(23):2060-2222
  • Ng AS, Sias AC, Pressman PS, Fong JC, Karydas AM, Zanto TP, De May M, Coppola G, Geschwind DH, Miller BL, Lee S. Young-onset frontotemporal dementia in a homozygous tau R406W mutation carrier. Annals of clinical and translational neurology 2015; 2(12):1124-1888
  • Ng AS, Rademakers R, Miller BL. Frontotemporal dementia: a bridge between dementia and neuromuscular disease. Ann N Y Acad Sci. 2015 Mar;1338:71-93
  • Ng AS, Kramer J, Centurion A, Dalmau J, Huang E, Cotter JA, Geschwind MD. Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis. J Neuroimmunol. 2015 Oct 15;287:31-5
  • Ng AS, Tan K. Methotrexate is effective for the treatment of neuromyelitis optica spectrum disorders in Asian patients. Clin Exp Neuroimmuno 6(2) May 2015
  • Ng AS, Sitoh YY, Zhao Y, Teng EW, Tan EK, Tan LC. Ipsilateral stroke in a patient with horizontal gaze palsy with progressive scoliosis and a subcortical infarct. Stroke. 2011 Jan;42(1):e1-3