Assoc Prof Au Wing Lok

Associate Professor Au Wing Lok is the Chief Executive Officer of Singapore's National Neuroscience Institute (NNI) and a Senior Consultant Neurologist. After graduating from the National University of Singapore, he completed his specialist training at NNI before advancing his expertise through a two-year Movement Disorders Fellowship at Canada's Pacific Parkinson's Research Centre. He also received specialised training in electrophysiology (the study of electrical activity in the nervous system) at Toronto Western Hospital, Canada.

Assoc Prof Au sees patients at NNI@TTSH and specialises in treating patients with Parkinson's disease and various movement disorders. He is trained in administering botulinum toxin injections (medication injections that help relax overactive muscles) for conditions such as:

• Hemifacial spasm (involuntary twitching or contractions of facial muscles)
• Blepharospasm (uncontrollable blinking or closure of the eyes)
• Dystonia (sustained muscle contractions causing unusual postures or repetitive movements)
• Spasticity (continuous muscle stiffness and tightness)

His research focuses on functional neuroimaging (advanced brain scanning techniques) and electrophysiology in Parkinson's disease, working to better understand how the brain functions in patients with movement disorders.

As the leader of NNI, A/Prof Au believes that employee wellness is key so that staff can give their best to their patients. He received the WorkWell Leaders Wellbeing CEO Award 2025 for prioritising staff mental wellbeing and creating a more resilient and supportive workplace at NNI.

• ​Fellowship (Neurophysiology in Movement Disorders), University of Toronto (Canada)
• Fellowship (Movement Disorders), University of British Columbia (Canada)
• FAMS (Neurology)
• MRCP (United Kingdom)
• MBBS (Singapore)

• ​Chief Executive Officer, National Neuroscience Institute
• Senior Consultant, Department of Neurology, National Neuroscience Institute (NNI@TTSH)
  
• Academic Chair, SingHealth Duke-NUS Neuroscience Academic Clinical Programme
• Deputy Programme Leader, Neurology Programme, Duke-NUS Medical School
• Associate Professor, SingHealth Duke-NUS Neuroscience Academic Clinical Programme, Singapore
• Clinical Senior Lecturer, Yong Loo Lin School of Medicine
• Adjunct Associate Professor, Lee Kong Chian School of Medicine
• Board Member, Parkinson Society Singapore

• ​SingHealth Quality Service Award, 2016 (Silver)
• Distinguished Team Award, SingHealth Excellence Award, 2015
• HMDP Fellowship Award, SingHealth, 2012
• NMRC Medical Research Fellowship Award, 2005
• HMDP Fellowship Award, NHG, 2004 - 2005

• ​Functional neuroimaging
• Electrophysiology in Parkinson's Disease

• ​Au WL, Seah IS, Li W, Tan LC. Effects of Age and Gender on Hand Motion Tasks. Parkinsons Dis. 2015;2015:862427. Epub 2015 May 24.
• Prakash BD, Sitoh YY, Tan LC, Au WL. Asymmetrical diffusion tensor imaging indices of the rostral substantia nigra in Parkinson's disease. Parkinsonism Relat Disord. 2012 Nov;18(9):1029-33. Epub 2012 Jun 16.
• Au WL, Zhou J, Palmes P, Sitoh YY, Tan LC, Rajapakse JC. Levodopa and the feedback process on set-shifting in Parkinson's disease. Hum Brain Mapp. 2012 Jan;33(1):27-39. Epub 2011 Mar 24.
• de la Fuente-Fernández R, Schulzer M, Kuramoto L, Cragg J, Ramachandiran N, Au WL, Mak E, McKenzie J, McCormick S, Sossi V, Ruth TJ, Lee CS, Calne DB, Stoessl AJ. Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. Ann Neurol. 2011;69(5):803-810. Epub 2011 Jan 18.
• Palmes P, Ang WT, Widjaja F, Tan LC, Au WL. Pattern mining of multichannel sEMG for tremor classification. IEEE Trans Biomed Eng. 2010 Dec;57(12):2795-805. Epub 2010 Sep 16.
• Srinivasan S, Lok AW. Valproate-induced reversible hemichorea. Mov Disord. 2010 Jul 30;25(10):1511-2.
• Palmer SJ, Lee PW, Wang ZJ, Au WL, McKeown MJ. theta, beta But not alpha-band EEG connectivity has implications for dual task performance in Parkinson's disease. Parkinsonism Relat Disord. 2010 Jul;16(6):393-7. Epub 2010 May 1.
• Au WL, Lei N, Oishi MM, McKeown MJ. L-dopa induces under-damped visually guided motor responses in Parkinson's disease. Exp Brain Res. 2010 May;202(3):553-9. Epub 2010 Feb 9.
• Wong YC, Au WL, Xu M, Ye J, Lim CC. Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. Arch Neurol. 2007 Jul;64(7):1034-7.
• Au WL, Calne DB. A reassessment of the Lewy body. Acta Neurol Taiwan. 2005 Jun;14(2):40-7.
• Au WL, Adams JR, Troiano AR, Stoessl AJ. Parkinson's disease: in vivo assessment of disease progression using positron emission tomography. Brain Res Mol Brain Res. 2005 Mar 24;134(1):24-33. Epub 2004 Nov 2.
• Au WL, Tan LCS, Tan AKY. Hemifacial spasm in Singapore: clinical characteristics and patients’ perceptions. Ann Acad Med Singapore 2004;33:324-328.
• Au WL, Das A, Tjia HTL. Myasthenia gravis in Singapore. Neurol J of South East Asia 2003;8:35-40.
• Au WL, Lim TC, Seow DC, Koh PL, Loh NK, Lim MS, Tan IK, Yee WC. Serial diffusion-weighted magnetic resonance imaging in adult-onset citrullinaemia. J Neurol Sci. 2003 May 15;209(1-2):101-4.