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Dr Wan Kai Rui

Dr Wan Kai Rui



National Neuroscience Institute

Specialty: Neurosurgery

Sub-specialties: General Neurosurgery

Conditions Treated by this Doctor:
General Neurosurgery.

Clinical Appointments

  • Consultant Neurosurgery Singapore General HospitalSingapore General Hospital
  • Consultant Department of Neurosurgery National Neuroscience InstituteNational Neuroscience Institute


​Dr Wan Kai Rui is a Consultant, Department of Neurosurgery at the National Neuroscience Institute.


  • ​FRCS (Surgical Neurology) Ed
  • Membership of the Royal Colleges of Surgeons of Great Britain and Ireland (MRCS)
  • Bachelor of Medicine/Bachelor of Surgery (MBBS)

Professional Appointments and Committee Memberships

  • ​Consultant, Department of Neurosurgery, National Neuroscience Institute


Research Interests


  • ​An Open label Randomized Trial to assess the efficacy of Tranexamic acid in reducing Post-operative recurrence of Chronic subdural Haemorrhage.
    Wan KR, Qiu LM, Saffari SE, Khong WXL, Ong CLJ, See A, Ng WH, King NK.
    Journal of Clinical Neuroscience 2019.
  • Automated detection of subthalamic nucleus in deep brain stimulation surgery for Parkinsons disease using microelectrode recordings and wavelet packet features.
    PA Karthick, Wan KR (shared first authorship), See, A, Dauwels J, King NK.
    J NeuroSci Methods 2020 Sep 1.
  • A review on microelectrode recording selection of features for machine learning in deep brain stimulation surgery for Parkinson’s disease.
    Wan KR, Maszczyk T, See A, Dauwels J, King NK.
    Clinical Neurophysiology 2019 January 130 (1): 145-154. doi:10.1016/j.clinph.2018.09.018. Epub 2018 Sep 25.
  • Detection of subthalamic nucleus using Time-frequency Features of Microelectrode recordings and Random Forest Classifier.
    PA Karthick, Wan KR, See, A, Dauwels J, King NK.
    Annual Int Conf IEEE Eng Med Biol Soc 2019.
  • Giant aneurysm arising from anomalous branch of the middle cerebral artery in a pediatric patient: Case report and review of the literature.
    Wan KR, Kirollos R, Lee HY, Low CYD, Ng LP, Seow WT, Low YYS.
    World Neurosurg 2019 Aug 128: 165-168.
  • Choice of valve type and poor ventricular catheter placement: Modifiable factors associated with ventriculoperitoneal shunt failure.
    Jeremiah KJ, Cherry CL, Wan KR, Toy JA, Wolfe R, Danks RA.
    J Clin Neurosci. 2016 May;27:95-8. doi: 10.1016/j.jocn.2015.07.026.
  • Synchronous multicentric glioblastoma with PNET and O subtypes: Possible pathogenesis.
    Wan KR, King NK, Low SY, Sitoh YY, Lee HY, Wong CF, Ng WH.
    Surg Neurol Int. 2014 Mar 4;5:31. doi: 10.4103/2152-7806.128182.
  • Uses and limitations of indocyanine green videoangiography for flow analysis in arteriovenous malformation surgery.
    Ng YP, King NK, Wan KR, Wang E, Ng I.
    J Clin Neurosci. 2013 Feb;20 (2):224-32. doi: 10.1016/j.jocn.2011.12.038.
    Received certificate for highly cited research in Journal of Clinical Neuroscience.
  • Factors affecting the accuracy of ventricular catheter placement.
    Wan KR, Toy JA, Wolfe R, Danks A.
    J Clin Neurosci. 2011 Apr;18(4):485-8. doi: 10.1016/j.jocn.2010.06.018.

Research Trials

  • ​An Open Label Randomized Trial to Assess the Efficacy of Tranexamic acid in Reducing Post-operative Recurrence of Chronic Subdural Haemorrhage - SingHealth Foundation Research