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Assoc Prof Prakash Kumar Manharlal

Assoc Prof Prakash Kumar Manharlal

MBBS, M.Med (Internal Medicine), MRCP (United Kingdom), FAMS (Neurology)

Head ＆ Senior Consultant

National Neuroscience Institute

Specialty/Department: Neurology, Neuroscience, Neurology

Clinical Interest: Parkinson's Disease, Movement Disorders, General Neurology

Conditions Treated by this Doctor:
Movement Disorders, Parkinson’s Disease.

Clinical Appointments

  • Head ＆ Senior Consultant Department of Neurology National Neuroscience InstituteNational Neuroscience Institute
  • Head ＆ Senior Consultant Neurology Singapore General HospitalSingapore General Hospital
  • Senior Consultant Neuroscience Sengkang General HospitalSengkang General Hospital

Profile

Assoc. Prof. Prakash Kumar obtained his undergraduate and postgraduate medical qualifications from Malaysia and subsequently underwent neurology specialist training in Singapore. Following that, he… View More +

Education

  • Fellowship in Parkinson’s and Movement Disorders (University of Toronto, Canada)
  • Specialist Accreditation in Neurology
  • Masters in Medicine (Internal Medicine) 
  • MRCP (United Kingdom)
  • MBBS (Malaya)

Professional Appointments and Committee Memberships

  • Head & Senior Consultant, Department of Neurology, National Neuroscience Institute (NNI@SGH)
  • Senior Consultant, Neurology, National Neuroscience Institute (NNI@SKH)
  • Programme Director, Parkinson and Movement Disorders, National Neuroscience Institute
  • Committee Member of Resident Advisory Committee (Neurology)
  • Program Director (Neurology Senior Residency) SingHealth Residency
  • Associate Professor and Research Mentor, Duke-NUS Medical School
  • Clinical Associate Professor, NUS Yong Loo Lin School of Medicine
  • Adjunct Associate Professor, Lee Kong Chien School of Medicine
  • Committee Member of International Association of Parkinsonism and Related Disorders (The Asian and Oceanic Educational Committee)
  • Executive Member of International Movement Disorder Society (AOS section)
  • Committee member of Clinical Neurophysiology Society of Singapore

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Awards

  • Covid-19 Resilience Medal 2023
  • 20 year - Long Service Award 2023
  • GCEO Excellence Awards, Outstanding Clinician Researcher Award 2018
  • SingHealth Graduate Medical Education, Program Director Service Appreciation Award 2017
  • Gold Award by Singapore Productivity Association (SPA) for Team Excellence in Innovation and Quality Circles held on 11 Nov 2015
  • SingHealth Team-Based HMDP fellowship in Melbourne 2014
  • Service with A Heart Award winner April 2013 in Singapore General Hospital
  • Singapore Health Quality Service Award (SHQSA) 2013, Gold Award
  • National Neuroscience Institute, Singapore Long Service Award 2012
  • Service Quality Partners Award Winner in October 2010 for Singapore General Hospital
  • Service Quality Partners Award Winner in March 2009 for Singapore General Hospital
  • Ministry of Health HMDP Award for fellowship in Toronto 2007-2008
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Research Interests

  • Motor and non-motor problems in Parkinson’s disease

Publications

  • Caffeine intake interacts with Asian gene variants in Parkinson's disease: a study in 4488 subjects. Ong YL, Deng X, Li HH, Narasimhalu K, Chan LL, Prakash KM, Au WL, Ratnagopal P, Tan LCS, Tan EK. Lancet Reg Health West Pac. 2023 Sep 4;40:100877. doi: 10.1016/j.lanwpc.2023.100877.
  • Ng, Yuen-Fann; Ng, Ebonne; Lim, Ee-Wei; Prakash KM; Tan, Louis CS; Tan, Eng-King. Case-control study of hypertension and Parkinson’s disease. NPJ Parkinson's Disease. 2021;7 (1);1-4.
  • Chao YX, Lee B, Ng EY, Lian MM, Chew EGY, Tandiono M, Li Z, Khor CC, Kumar P, Tan LCS, Foo JN, Tan EK. Association analysis of PSAP variants in Parkinson's disease patients. Brain : A Journal Of Neurology, 144(1):e9; 2021-02.
  • Koh Jasmine Shimin; De Silva Deidre Anne; Quek Amy May Lin; Chiew Hui Jin; Tu Tian Ming; Seet Christopher Ying Hao; Hoe Rebecca Hui Min; Saini Monica; Hui Andrew Che-Fai; Angon Jasmyn; Justin Ruixin Ker, Ming Hui Yong, Yihui Goh, Wai-Yung Yu, Tchoyoson Choie Cheio Lim, Benjamin Yong Qiang Tan, Kay Wei Ping Ng, Leonard Leong Litt Yeo, Yu Zhi Pang, Prakash KM, Aftab Ahmad, Terrence Thomas, David Chien Boon Lye, Kevin Tan, Thirugnanam Umapathi. Neurology of COVID-19 in Singapore Journal of the Neurological Sciences. 2020;418, 117118.
  • Foo JN, Chew EGY, Chung SJ, Peng R, Blauwendraat C, Nalls MA, Mok KY, Satake W, Toda T, Chao Y, Tan LCS, Tandiono M, Lian MM, Ng EY, Prakash KM, Au WL, Meah WY, Mok SQ, Annuar AA, Chan AYY, Chen L, Chen Y, Jeon BS, Jiang L, Lim JL, Lin JJ, Liu C, Mao C, Mok V, Pei Z, Shang HF, Shi CH, Song K, Tan AH, Wu YR, Xu YM, Xu R, Yan Y, Yang J, Zhang B, Koh WP, Lim SY, Khor CC, Liu J, Tan EK. Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. Jama Neurology. 2020; 77(6):746-754.
  • Ng ASL, Lim WK, Xu Z, Ong HL, Tan YJ, Sim WY, Ng EYL, Teo JX, Foo JN, Lim TCC, Yu WY, Chan LL, Lee HY, Chen Z, Lim EW, Ting SKS, Prakash KM, Tan LCS, Yi Z, Tan EK. NOTCH2NLC GGC Repeat Expansions Are Associated with Sporadic Essential Tremor: Variable Disease Expressivity on Long-Term Follow-up. Annals Of Neurology. 2020; 88(3):614-618.
  • Chew EGY, Tan LCS, Au WL, Prakash KM, Liu J, Foo JN, Tan EK. ITPKB and ZNF184 are associated with Parkinson’s disease risk in East Asians. Neurobiol Aging. 2020;86(201):e15-17.
  • Deng, Xiao; Xiao, Bin; Li, Hui-Hua; Ng, Ebonne; Lo, Yew-Long; Tan, Eng-King; Prakash KM. Four-Year Longitudinal Study of Motor and Non-motor Symptoms in LRRK2-Related Parkinson's Disease. Frontiers in Neurology. 2020.10;3389.
  • Ng ASL, Tan YJ, Lu Z, Ng EYL, Ng SYE, Chia NSY, Setiawan F, Xu Z, Tay KY, Prakash KM, Au WL, Tan EK, Tan LCS. Plasma alpha-synuclein detected by single molecule array is increased in PD. Annals Of Clinical And Translational Neurology. 2019;6(3):615-619.
  • Chew EGY, Liany H, Tan LCS, Au WL, Prakash KM, Annuar AA, Chan AYY, Lim SY, Mok V, Chung SJ, Song K, Liu J, Foo JN, Tan EK. Evaluation of novel Parkinson's disease candidate genes in the Chinese population. Neurobiology Of Aging. 2019;74:235.e1-235.e4.
  • Wu J, Lim EC, Nadkarni NV, Tan EK, Kumar PM. The impact of levodopa therapy-induced complications on quality of life in Parkinson’s disease patients in Singapore. Scientific Reports. 2019;9(1):9248.
  • Tan MJM, Lim EC, Nadkarni NV, Lye WK, Tan EK, Prakash KM. The characteristics of patients associated with high caregiver burden in Parkinson’s disease in Singapore. Frontiers in Neurology-Movement Disorders. DOI: 10.3389/fneur.2019.00561.
  • Foo JN, Tan LC, Au WL, Prakash KM, Liu J, Tan EK. No association of DNM3 with age of onset in Asian Parkinson’s disease. Eur J of Neurol. 2019. 26(5):827-9.
  • Tan D, Puan YH, Balakrishnan S, Scully A, Bower KJ, Prakash KM, Tan EK, Chew JS, Poh E, Tan SB, Clark RA. Automated analyis of gait and modified timed up and go using the Microsoft Kinect in people with Parkinson’s disease: associations with physical outcome measures. Med  Biol Eng Comput. 2019. 57(2):369-77.
  • Ng ASL, Ng EYL, Tan YJ, Prakash KM, Au WL, Tan LCS, Tan EK. Case –control analysis of LRRK2 protective variants in essential tremor. Sci Rep. 2018. 28;8(1):5346.
  • Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK. Genome-wide association study of Parkinson's disease in East Asians. Hum Mol Genet. 2017 Jan;26(1):226-232. 
  • Chao YX, Lin Ng EY, Tio M, Kumar P, Tan L, Au WL, Yih Y, Tan EK. Essential tremor linked TENM4 mutation found in healthy Chinese individuals. Parkinsonism Relat Disord. 2016 Oct;31:139-140.
  • Prakash KM, Nadkarni NV, Lye WK, Yong MH, Chew LM, Tan EK. The impact of non-motor symptoms on the quality of life of Parkinson’s disease patients: a longitudinal study. Eur J Neurol. 2016 May;23(5):854-60.
  • Foo JN, Chung SJ, Tan LC, Liany H, Ryu HS, Hong M, Koh TH, Irwan ID, Au WL, Prakash KM, Aung T, Cheng CY, Chong SA, Khor CC, Lee J, Tai ES, Vithana EN, Wong TY, Song K, Liu J, Tan EK. Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease. Mov Disord. 2016 Apr;31(4):484-7.
  • Kumar PM, Paing SS, Li H, Pavanni R, Yuen Y, Zhao Y, Tan EK. Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson's Disease. Sci Rep. 2015 Nov 2;5:15492.
  • Deng X, Xiao B, Li HH, Lo YL, Chew LM, Prakash KM, Tan EK. Sexual dysfunction is associated with postural instability gait difficulty subtype of Parkinson's disease. J Neurol. 2015 Nov;262(11):2433-9.
  • Prakash KM, Nadkarni NV, Lye WK, Yong MH, Chew LM, Tan EK. A longitudinal study of non-motor symptom burden in Parkinson's disease after a transition to expert care. Parkinsonism Relat Disord. 2015 Aug;21(8):843-7.
  • Chao YX, Ng EY, Li H, Nagaendran K, Yih Y, Chong MS, Prakash KM, Tan L, Au WL, Zhao Y, Zhou ZD, Tio M, Pavanni R, Tan EK. Association Analysis of COQ2 Variant in Dementia and Essential Tremor. Parkinsons Dis. 2015;2015:926280.
  • Chao YX, Ng EY, Tan L, Prakash KM, Au WL, Zhao Y, Tan EK. Lrrk2 R1628P variant is a risk factor for essential tremor. Sci Rep. 2015 Mar 12;5:9029.
  • Foo JN, Liany H, Tan LC, Au WL, Prakash KM, Liu J, Tan EK. DNAJ mutations are rare in Chinese Parkinson's disease patients and controls. Neurobiol Aging. 2014;35(4):935. e1-2.
  • Foo JN, Tan LC, Liany H, Koh TH, Irwan ID, Ng YY, Ahmad-Annuar A, Au WL, Aung T, Chan AY, Chong SA, Chung SJ, Jung Y, Khor CC, Kim J, Lee J, Lim SY, Mok V, Prakash KM, Song K, Tai ES, Vithana EN, Wong TY, Tan EK, Liu J. Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. Hum Mol Genet. 2014;23(14):3891-7.
  • Ting SK, Hameed S, Prakash KM. Ganser Symptoms in a Chinese Speaking
  • Corticobasal Syndrome (CBS) Patient. Ann Acad Med Singapore. 2014;43(3):197-9.
  • Wu YR, Foo JN, Tan LC, Chen CM, Prakash KM, Chen YC, Bei JX, Au WL, Chang CW, Wong TY, Liu JJ, Zhao Y, Tan EK. Identification of a novel risk variant in the FUS gene in essential tremor. Neurology. 2013 Aug 6;81(6):541-4.
  • Foo JN, Liany H, Bei JX, Yu XQ, Liu J, Au WL, Prakash KM, Tan LC, Tan EK. A rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease. Neurobiol Aging. 2013 Dec;34(12):2890.e13-5.
  • Seng Ting SK, Chong MS, Kandiah N, Hameed S, Tan L, Au WL, Prakash KM, Pavanni R, Lee TS, Foo JN, Bei JX, Yu XQ, Liu JJ, Zhao Y, Lee WL, Tan EK. Absence of A673T amyloid-β precursor protein variant in Alzheimer's disease and other neurological diseases. Neurobiol Aging. 2013 Oct;34(10):2441.e7-8.
  • Tan EK, Foo JN, Tan LC, Au WL, Prakash KM, Ng E, Ikram MK, Wong TY, Liu J, Zhao Y. SLC1A2 variant associated with Essential Tremor but not Parkinson’s disease in Chinese. Neurology 2013 Apr 23;80(17):1618-9.
  • Yong MH, Allen JC, Prakash KM, Tan EK. Differentiating non-motor symptoms in Parkinson’s disease from controls and hemifacial spasm. PLoS One. 2013;8(2):e49596.
  • Peeraully T, Tan SF, Fook-Chong SM, Prakash KM, Tan EK. Headache in hemifacial spasm patients. Acta Neurol Scand. 2013 May;127(5):e24-7.
  • Zhao Y, Ho P, Prakash KM, Foo JN, Liu JJ, Au WL, Tan LC, Tan EK. Analysis of EIF4G1 in Parkinson's disease among Asians. Neurobiol Aging. 2013 Apr;34(4):1311.e5-6.
  • Zhao Y, Gopalai AA, Ahmad-Annuar A, Teng EW, Prakash KM, Tan LC, Au WL, Li HH, Lim SY, Lim SK, Chong YB, Tan LP, Ibrahim NM, Tan EK. Association of HLA locus variant in Parkinson's disease. Clinical Genetics. 2013 Nov;84(5):501-4.
  • Yip CW, Cheong PW, Green A, Prakash PK, Fook-Cheong SK, Tan EK, Lo YL. A prospective pilot study of repetitive transcranial magnetic stimulation for gait dysfunction in Vascular Parkinsonism. Clin Neurol Neurosurg. 2013 Jul;115(7):887-91.
  • Wu YR, Tan LC, Fu X, Chen CM, Au WL, Chen L, Chen YC, Prakash KM, Zheng Y, Lee-Chen GJ, Zhao Y, Zeng JS, Tan EK, Pei Z. LRRK2 A419V is not associated with Parkinson's disease in different Chinese populations. PLoS One. 2012;7(7):e36123.
  • Ahmad MT, Hameed S, Prakash KM. Spontaneous Intracranial Hypotension with Bilateral Subdural Hemorrhage: Is Conservative Management Adequate? Annals of Indian Academy of Neurology. 2013 Jan;16(1):94-6.
  • Ting SKS, Prakash KM. A rare cause of cerebellar ataxia syndrome: Superficial siderosis of central nervous system. Acta Neurol Taiwan. 2011 Dec;20(4):257-61.
  • Prakash KM, Tan EK. Clinical evidence linking coffee and tea intake with Parkinson’s disease. Basal Ganglia. 2011 1(3):127-131.
  • Ahmad MT, Chan LL, Prakash KM. Frontal lobe syndrome due to “a bunch of grapes”. Annals Academy of Medicine. 2011 Jul;40(7):336-2.
  • Marras C, Schuele B, Munhoz RP, Rogaeva EA, Langston JW, Kasten M, Meaney C, Klein C, Wadia PM, Lim SY, Chuang RSI, Zadikoff C, Steeves T, Prakash KM, de Bie RMA, Adeli G, Thomsen T, Johansen KK, Teive H, Asante A, Reginold W, Lang AE. LRRK2-associated Parkinson’s disease: Phenotype in parkinsonian and non-parkinsonian G2019S mutation carriers. Neurology 2011 Jul 26;77(4):325-33.
  • Wu YW, Prakash KM, Rong TY, Li HH, X Qin, Tan LC, Au WL, Ding JQ, Chen SD,  Tan EK. Lingo2 associated with essential tremor and Parkinson’s disease. Hum Genet. 2011 Jun;129(6):611-5.
  • Ahmad MT, Yip CW, Prakash KM. Reversible hyperkinetic movement disorder related to quetiapine withdrawal: a case report. Proceedings of Singapore Healthcare.2011; 19(4):347-8.
  • Prakash KM. An overview of surgical therapy for movement disorders. (review). Proceedings of Singapore Healthcare.2011; 19(4):303-11.
  • Wu YR, Tan EK, Chen CM, Kumar PM, Lee-Chen GJ, Chen ST. Genetic analysis of "leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1(LINGO1)" in two independent Chinese parkinson's disease populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan;156(1):99-103.
  • Prakash KM, Ting SKS, Ahmad MT. Unusually increased arm swing in an apraxic upper limb in corticobasal syndrome. Parkinsonism and Related Disorders. 2011 Feb;17(2):126-7
  • Prakash KM, Tan EK. Development of biomarkers for Parkinson’s disease. Expert Review of Neurotherapeutics. 2010 Dec;10(12):1811-25.
  • Prakash KM, Kek PC. Hyperthyroidism “masked” the levodopa response in newly diagnosed Parkinson’s disease patients. Parkinsonism and Related Disorders. 2010 Dec;16(10):691-2.
  • Tan EK, Kwok HK, Tan LC, Zhao WT, Prakash KM, Au WL, Pavanni R, Ng YY, Satake W, Zhao Y, Toda T, Liu JJ. Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus. Neurology. 2010 Aug 10;75(6):508-12
  • Ahmad MT, Prakash KM. Reversible Hyperkinetic Movement Disorder Associated With Quetiapine Withdrawal. Movement Disorders. 2010 Jul 15;25(9):1308-9.
  • Tan EK, Peng R, Teo YY, Tan L, Angeles D, Ho P, Chen ML, Lin CH, Mao XY, Prakash KM, Liu JJ, Au WL, Le WD, Jankovic J, Burgunder JM, Zhao Y, Wu RM. Multiple LRRK2 variants modulate risk of Parkinson’s Disease: a multicenter study in Chinese. Human Mutation. 2010 May;31(5):561-8.
  • Tan EK, Ho P, Tan L, Prakash KM, Zhao Y. PLA2G6 mutations and Parkinson’s Disease. Annals of Neurol. 2009;67(1):147-8.
  • Tan EK, Teo YY, Prakash KM, Li R, Lim HQ, Angeles D, Tan L, Au WL, Yih Y, Zhao Y. LINGO1 variant increases risk of familial Essential Tremor. Neurology . 2009 Oct 6;73(14):1161-2.
  • Tan EK, Lin CH, Tai CH, Tan LC, Chen ML, Li R, Lim HQ, Pavanni R, Yuen Y, Prakash KM, Zhao Y, Wu RM. Non-synonymous GIGYF2 variants in Parkinson's disease from two Asian populations. Hum Genet. 2009 Sep;126(3):425-30
  • Cheung RY, Lee LH, Prakash KM, Wong GC. A patient with extramedullary acute myeloid leukaemia involving brachial plexus: case report and review of literatures. Turkish Journal of Hematology. 2008;25(2):98-100.
  • Prakash KM, Miyasaki J. Troubling tremors: All that shakes isn’t Parkinson’s. Parkhurst Exchange. 2008 Jan:54-55.
  • Tan EK, Tan LC, Lim HQ, Li R, Tang M, Yih Y, Pavanni R, Prakash KM, Fook-Chong S, Zhao Y. LRRK2 R1628P increases risk of Parkinson's disease: replication evidence. Hum Genet. 2008 Oct;124(3):287-8.
  • Lo YL, Chan LL, Prakash KM, Ratnagopal P. An unusual overlap syndrome with features of Bickerstaff's brainstem encephalitis and the Guillain - Barré syndrome. Journal of Clinical Neuromuscular Disease. 2008 (in press)
  • Ngeow JYY, Prakash KM, Chowbay B, Quek ST, Choo SP. Capecitabine- induced oromandibular dystonia: A case report and literature review. Acta Oncologica. 2008;47(6):1161-5.
  • Prakash KM, Lang AE. Reversible dopamine agonist induced anterocollis in a multiple system atrophy patient. Movement Disorders. 2007 Nov;22(15):2292-3.
  • Prakash KM, Tan EK. Validity of family history in essential tremor.
  • Parkinsonism and Related Disorders. 2008;14(2):151-3.
  • Prakash KM. Improving your balance: a delicate act. Parkinson’s disease society of Singapore: Parkinson’s News. 2007 May.
  • Tan EK, Prakash KM, Fook-Chong S, Yih Y, Chua E, Lum SY, Wong MC, Pavanni R, Y Zhao. DRD3 variant and risk of essential tremor. Neurology. 2007 Mar;68(10):790-1.
  • Prakash KM, Puvanendran R, Ratnagopal P, Lo YL. Mycophenolate mofetil as an adjunctive therapy in severe myasthenia gravis: The Singapore experience. Journal of Clinical Neuroscience. 2007 Mar;14(3):278-81.
  • Prakash KM, Fook-Chong S, Leoh TH, Dan YF, Nurjannah S, Tan YE, Lo YL. Sensitivities of sensory nerve conduction study parameters in carpal tunnel syndrome. Journal of Clinical Neurophysiology. 2006 Dec;23(6):565-567.
  • Prakash KM, Fook-Choong S, Yuen Y, Tan EK. Exploring the relationship between caffeine intake and essential tremor. Journal of the Neurological Sciences.2006 Dec;251(1-2):98-101.
  • Tan EK, Lum SY, Prakash KM. Clinical features of Childhood Onset Essential Tremor. Parkinsonism and Related Disorders. 2006 Dec;13(12):1302-5.
  • Prakash KM, Lum SY, Fook-Choong S, Tan EK. Knowledge about the genetics of essential tremor in patients and their relatives. European Journal of Neurology. 2006 Nov;13(11):1266-9.
  • Prakash KM, Ratnagopal R. Diffuse pachymeningeal enhancement. Journal of Clinical Neuroscience. 2006 Oct;13(8):848.
  • Prakash KM, Leoh TH, Dan YF, Nurjannah S, Tan YE, Xu LQ, Lo YL. The lower subscapular nerve conduction studies in normal subjects. Journal of the Neurological Sciences 2006 Aug;247(1):77-80.
  • Tan EK, Fook-Chong S, Lum SY, Gabriel C, Koh KK, Prakash KM, Louis ED. Non-motor manifestations in essential tremor: Use of a validated instrument to evaluate a wide spectrum of symptoms. Parkinsonism and Related Disorders. 2005 Sep;11(6):375-80.
  • Lo YL, Prakash KM, Leoh TH, Tan YE, Dan YF, Ratnagopal P. Pectoral nerve conduction studies: technique in normal subjects and evaluation of brachial plexopathy. Archives of Physical Medicine and Rehabilitation. 2005 Aug;86(8):1702-5.
  • Prakash KM, Lo YL The role of clinical neurophysiology in bioterrorism. Acta Neurologica Scandinavica. 2005 Jan;111(1):1-6.
  • Lo YL, Prakash KM, Leoh TH, Tan YE, Dan YF, Xu LQ, Ratnagopal P. Posterior antebrachial cutaneous nerve conduction study in radial neuropathy. Journal of Neurological Science. 2004 Aug;223(2):199-202.
  • Prakash KM, Lo YL. SUNCT syndrome in association with persistent Horner syndrome in a Chinese patient. Headache. 2004 Mar;44(3):256-8.
  • Prakash KM, Leoh TH, Dan YF, Nurjannah S, Tan YE, Xu LQ, Lo YL. Posterior antebrachial cutaneous nerve conduction studies in normal subjects. Clinical Neurophysiology. 2004 Apr;115(4):752-4.
  • Prakash KM, Raymond AA. The use of nerve conduction studies in determining the short-term outcome of Bell's palsy. Medical Journal of Malaysia. 2003 Mar;58(1):69-78.
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Research Trials

  • Project Lead: Temasek Foundation Parkinson Disease Community Care Programme (TFPDCCP) funded by Temasek Foundation SGD $ 1,568,420.00.
  • Project Lead: One Stop Integrated Care Model for Parkinson’s and Parkinson’s Mobile Application Development funded by SINGHEALTH FUND - NNI SGD $ 739,656.00. 
  • Co-Investigator: Microbiome and Biomarkers in Parkinson’s disease. (CIRB: 2016/2834)
  • Site Principal Investigator: Real-time Freezing of Gait (FOG) detection and biofeedback device to facilitate rehabilitation in patients with Parkinsonism and related disorders. NUS – NNI Research Collaborative Grant $150,000. (CIRB: 2016/2743)
  • Principal Investigator: One-stop integrated care for Parkinson’s disease: A randomized crossover study. (CIRB: 2016/2467)
  • Co-Investigator: The role of monocytes in the pathogenesis of Parkinson’s disease. (CIRB: 2016/2182)
  • Principal Investigator: The impact of motor and non-motor symptoms on disability, falls and quality of life on people with Parkinson's disease. (CIRB: 2015/2835)
  • Co-Investigator. Pilot randomized controlled study of the efficacy of spinal magnetic stimulation for refractory constipation. (CIRB: 2015/2717)
  • Principal Investigator: The impact of non-motor symptoms Parkinson's disease on quality of life, economic and caregiver burden. Ministry of Health HSR grant $98,974. (HSRG12MAY007)
  • Principal Investigator. LRRK2 genetic variants and caffeine in Parkinson’s disease. NIG / NMRC grant $200,000. (NIG/NMRC 2012/14).
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