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Dr Ng Wai Hoe from National Neuroscience Institute

Assoc Prof Ng Wai Hoe

​MBBS, MBA, MD (NUS), FRACS (Neurosurgery), FAMS

Medical Director and Senior Consultant

National Neuroscience Institute

Specialty: Neurosurgery

Sub-specialties: Functional Neurosurgery, Neuro-Oncology, Epilepsy Surgery, Neurotrauma, General Neurosurgery

Conditions Treated by this Doctor:
Brain Tumours, Epilepsy Surgery, Functional Neurosurgery, General Neurosurgery, Neurotrauma.

Clinical Appointments

  • Senior Consultant Neurosurgery Singapore General HospitalSingapore General Hospital
  • Senior Consultant Department of Neurosurgery National Neuroscience InstituteNational Neuroscience Institute
  • Director, Neurosurgical Oncology Programme National Neuroscience InstituteNational Neuroscience Institute
  • Medical Director National Neuroscience InstituteNational Neuroscience Institute
  • Deputy Group Director, Medical Board, SingHealth SingHealthSingHealth

Academic Appointments

  • Academic Chair (SingHealth Duke-NUS Neuroscience ACP) SingHealth Duke-NUS Neuroscience Academic Clinical Programme

Profile

​Dr Wai-Hoe Ng is the Medical Director of the National Neuroscience Institute and Academic Chair of the SingHealth Duke-NUS Neuroscience Academic Clinical Program. He is also the Deputy Chairman of the SingHealth Medical Board.

Dr Ng is a neurosurgeon with a subspecialty practice focused on Neurosurgical Oncology (Brain Tumours), Stereotactic and Functional Neurosurgery and Epilepsy Surgery.

Education

  • ​MBBS
  • MBA 
  • MD (NUS)
  • FRACS (Neurosurgery)
  • FAMS

Professional Appointments and Committee Memberships

  • Medical Director, National Neuroscience Institute
  • Academic Chair, SingHealth Duke-NUS Neuroscience Academic Clinical Programme
  • Deputy Group Chairman, Medical Board, SingHealth
  • Senior Consultant, Department of Neurosurgery, National Neuroscience Institute
  • Director, Neurosurgical Oncology Programme, National Neuroscience Institute
  • Visiting Consultant, Neurosurgery Service, KK Women’s and Children’s Hospital
  • Visiting Consultant, Division of Neurosurgery, Changi General Hospital
  • Co-Director, Brain and Behaviour, Duke-NUS Medical School
  • Associate Professor (Regular Rank), Duke-NUS Medical School

Awards

  • ​Yahya Cohen Memorial Lectureship 2017 (College of Surgeons)
  • GCEO Outstanding Clinician Award 2014
  • Sugita Scholarship 2010 (Nagoya University)

Publications and Research Trials

  • Simultaneous Functional Photoacoustic Microscopy and Electrocorticography Reveal the Impact of rtPA on Dynamic Neurovascular Functions after Cerebral Ischemia. (Bandla Aishwarya, Liao Lun-De, Chan Su Jing, Ling Ji Min, Liu Yu-Hang, Shih Yen-Yu, Pan Han-Chi, Wong Peter Tsun Hon, Lai Hsin-Yi, King Nicolas, Chen You-Yin, Ng Wai Hoe, Thakor, Nitish V) In Press, Journal of Cerebral Blood Flow and Metabolism.
  • The Fluoropen: A Simple Low Cost Device to Detect Intraoperative Fluorescein Fluorescence in Stereotactic Needle Biopsy of Brain Tumours. (Thien A, Rao JP, Ng WH, N KKK) Acta Neurochir (2017) 159(2):371-375.
  • Independent Mobility Achieved through a Wireless Brain-Machine Interface. (Libedinsky C, So R, Xu Z, Kyar TK, Ho D, Lim C, Chan L, Chua Y, Yao L, Cheong JH, Lee JH, Vishal KV, Guo Y, Chen ZN, Lim LK, Li P, Liu L, Zou X, Ang KK, Gao Y, Ng WH, Han BS, Chng K, Guan C, Je M, Yen SC) PLoS One (2016) 1;11(11):e0165773.
  • The Australasian contribution to the development of neurosurgery in Singapore. (Foo AS, Khoo JC, Ong PL, Ho KH, Seow WT, Ng WH, Yeo TT) ANZ J Surg (2016) 86(12):961-962.
  • ”Subarachnoid cyst” after evacuation of chronic subdural hematoma: Case report of an unusual postoperative morbidity. (Low YY Sharon, Ng Wai Hoe) Asian J Neurosurg (2016) 11(3):316.
  • Mechanical Confinement Triggers Glioma Linear Migration Dependent On Formin, FHOD3. (Monzo P, Chong YK, Guetta-Terrier C, Krishnasamy A, Sathe SR, Yim EK, Ng WH, Ang BT, Tang C, Ladoux B, Gauthier NC, Sheetz MP) Mol Biol Cell. (2016) 15;27(8):1246-1261.
  • Treatment of severe, disabling spasticity with continuous intrathecal baclofen therapy following acquired brain injury: the experience of a tertiary institution in Singapore. (Wang ZM, Law JH, King NK, Rajeswaran DK, Soh S, Rao JP, Ng WH, Chua KS) Singapore Med J (2016) 57(1):8-12.
  • Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme. (Yulyana Y, Tovmasyan A, Ho IA, Sia KC, Newman JP, Ng WH, Guo CM, Hui KM, Batinic-Haberle I, Lam PY) Stem Cell Rev (2016) 12(1):140-155.
  • ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis. (Chong YK, Sandanaraj E, Koh LW, Thangaveloo M, Tan MS, Koh GR, Toh TB, Lim GG, Holbrook JD, Kon OL, Nadarajah M, Ng I, Ng WH, Tan NS, Lim KL, Tang C, Ang BT) J Natl Cancer Inst. 2015 Nov 7;108(2). pii: djv326. doi: 10.1093/jnci/djv326. Print 2016 Feb.
  • Serum procalcitonin is a marker for prediction of readmission from an intermediate care to an acute care hospital in neurosurgical patients. (Lim JX, King N, Low S, Ng WH) Surg Neurol Int (2015) 6:144.
  • Assessment of neurovascular dynamics during transient ischemic attack by the novel integration of micro-electrocorticography electrode array wit functional photoacoustic microscopy. (Liu YH, Liao LD, Tan SS, Kwon KY, Ling JM, Bandia A, Shih YI, Tan ET, Li W, Ng WH, Lai HY, Chen YY, Thakor NV) Neurobiol Dis (2015) 82:455-465.
  • Awake craniotomy using electromagnetic navigation technology without rigid pin fixation. (Morsy AA, Ng WH) J Clin Neurosci (2015) 22(11):1827-1829.
  • Outcomes of Subdural Haematoma Drainage in Nonagenarians and Centenarians: A Multicentre Study. (Lester Lee, Justin Ker, Hui Yu Ng, Thangaraj Munusamy, Nicolas Kon Kam King, Dinesh Kumar, Wai Hoe Ng) J Neurosurg (2015) Jul 10:1-6.
  • Combined treatment of Nimotuzumab and paramycin is effective against temozolamide-resistant human gliomas regardless of the EGFR mutation status. (Chong DQ, Toh XY, Ho IA, Sia KC, Newman JP, Yulyana Y, Ng WH, Lai SH, Ho MM, Dinesh N, Tham CK, Lam PY) BMC Cancer (2015) 15:255.
  • Re-do craniotomy for recurrent glioblastoma. (Morsy AA, NgWH) CNS Oncol (2015) 4(2):55-57.
  • An unusual presentation of primary malignant B-cell-type dural lymphoma. (Yin Yee Sharon Low, Siang Hui Lai, Wai Hoe Ng) Singapore Med J (2014)  55(11): e187-e190.
  • Value of routine early post-operative computed tomography in determining short-term functional outcome after drainage of chronic subdural haematoma: an evaluation of residual volume. (Hui Yu Ng, Wai Hoe Ng, Nicolas KK King)  Surg Neurol Int. (2014) 5:136.
  • A Computed Tomography Morphometric Study of Occipital Bone and C2 Pedicle Anatomy for Occipital-Cervical Fusion.  (Nicolas K.K. King, Tiruchelvarayan Rajendra, Ivan Ng, Wai Hoe Ng) Surg Neurol Int. (2014) 28:5(Suppl 7):S380-3.
  • A 58 year-old male with halluciations and ataxia. (Yee Lin Tang, Wai Hoe Ng, Yih Yian Sitoh, Hwei Yee Lee, Wai Ming Yap, Khoon Leong Chuah) Brain Pathology (2014) 24:301-302.
  • Synchronous multicentric glioblastoma with PNET and O Subtypes: Possible pathogenesis. (Wan KR, King NK, Low SY, Sitoh YY, Lee HY, Wong CF, Ng WH) Surg Neurol Int (2014) 5:31.
  • MicroRNA as potential modulators in chemoresistant high-grade gliomas. (Sharon Yin Yee Low, Yoon Khei Ho, Heng-Phon Too, Celestial Therese Yap, Wai Hoe Ng) J Clin Neurosci (2014) 21(3):395-400.
  • The potential application of transcriptionally regulated oncolytic herpes simplex virusfor human cancer treatment. (Miao L, Fraefel C, Sia KC, Newman JP, Mohamed-Bashir SA, Ng WH, Lam PY) Br J Cancer (2014) 110(1):94-106.
  • Tension Pneumocephalus. (Pulickal GG, Sitoh YY, Ng WH) Singapore Med J (2014) 55(3):e46-48.
  • High-frequency Stimulation of Globus Pallidus Interna modulates GFRα1 Gene Expression in Basal Ganglia. (Duncan Xun Kiat Ho, Jia Yi Tan, Yong Chee Tan, Heng PhonToo, Wai Hoe Ng). J Clin Neurosci (2014) 21(4): 657-660.
  • Primary human chorionic gonadotrophin secreting germinoma of the corpus callosum. (Foo Song Chuan Aaron, Chong  QQ Dawn, Chang TE Kenneth, Ng Wai Hoe, Soh Shui Yen, Tham Chee Kian).  Surg Neurol Int (2013) 4:137.
  • An S-shaped Incision For The Insertion of Deep Brain Stimulators. (Lester Lee, John Thomas, Wai Hoe Ng). Acta Neurochir (2013) 155(9):1671-1674.
  • A case of large B-cell intravascular lymphoma in the brain. (Lee Ping Gan, Wei Seong Ooi, Hwei Yee Lee, Wai Hoe Ng).  Surg Neurol Int (2013) 4:99.
  • A Distinct Reactive Oxygen Species Profile Confers Chemoresistance in Glioma-Propagating Cells and Associates with Patient Survival Outcome. (Koh LW, Koh GR, Ng FS, Toh TB, Sandanaraj E, Chong YK, Phong M, Tucker-Kellogg G, Kon OL, Ng WH, Ng IH, Clement MV, Pervaiz S, Ang BT, Tang CS). Antioxid Redox Signal. (2013) 19(18):2261-2279.
  • Carbenoxolone Enhances TRAIL-Induced Apoptosis Through the Upregulation of Death Receptor 5 and Inhibition of Gap Junction Intercellular Communication in Human Glioma. (Yulyana Y, Endaya BB, Ng WH, Guo CM, Hui KM, Lam PY, Ho IA). Stem Cells Dev. (2013)1;22(13):1870-1882.
  • A promising light for an impossible disease: miRNAs in malignant gliomas. (Yin Yee Sharon Low, Wai Hoe Ng). CNS Oncology (2013) 2(2):107-109.
  • Cortical Reorganization of Motor Functional Areas in Cerebral Arteriovenous Malformations (Lester Lee, Yih Yian Sitoh, Ivan Ng, Wai Hoe Ng) J Clin Neurosci (2013) 20(5):649-653.
  • Combined temozolomide and radiation as an initial treatment for anaplastic glioma. (Tham CK, See SJ, Tan SH, Lim KH, Ng WH, Thomas J, Chong DQ, Chua ET). Asia Pac J Clin Oncol. (2013) 9(3):220-225.
  • Rosette-Forming Glioneuronal Tumour of the Fourth Ventricle Arising in the Cerebellar Hemisphere: Diagnostic Challenges Including Cytological Features in Intra-Operative Squash Preparations. (DWQ Lian, HY Lee, WH Ng, KL Chuah, WM Yap) Pathology-Journal of the RCPA (2013) 45:S75..
  • Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis. (Ho IA, Toh HC, Ng WH, Teo YL, Guo CM, Hui KM, Lam PY) Stem Cells (2013) 31(1):146-155.
  • Brain metastases as a cause of malignant cerebrospinal fluid ascites: case report and review of the literature.  (Yin Yee Sharon Low , John Thomas , Wei Keat Wan , Wai Hoe Ng). CNS Oncology (2012) 1(1):29-37.
  • Anaplastic supratentorial cortical ependymoma presenting as a butterfly lesion. (Ng DW, King NK, Foo AS, Sitoh Y, Lee HY, Ng WH). Surg Neurol Int (2012) 3: 107.
  • Incidence of Extracranial Metastasis in Glioma- a Single Institutional Experience (Amitendu Sekhar, David Siu Kei Mak, Ji Min Ling, Khoon Leong Chuah, Wai Hoe Ng)  J Clin Neurosci  (2012) 19(11):1511-1515.
  • A typical Teratoid Rhabdoid Tumor- Report from a Children’s Cancer Centre in Singapore. (Shui Yen Soh, Mei Yoke Chan, Wan Tew Seow, Kenneth Chang, Wai Hoe Ng, Ah Moy Tan) Neuro-oncology (2012) 14:3-4.
  • Progenitor-like traits contribute to patient survival and prognosis in oligodendroglial tumors. (Esther Hui-Ling Ting, Mark Phong, Geraldene Rong-Hui Koh, Swee Seong Wong, Siew Hong Leong, Oi Lian Kon, Joan Siew-Ching Lee, Tan Boon Toh, Felicia Soo-Lee Ng, Greg Tucker-Kellogg, Wai Hoe Ng, Ivan Ng, Carol Tang, Beng Ti Ang) Clin Cancer Res. (2012) 1;18(15):4122-4135.
  • Tumor tropism of intravenously injected human-induced pluripotent stem cell-derived neural stem cells and their gene therapy application in a metastatic breast cancer model (Jing Yang, Dang Hoang Lam, Sally Sallee Goh, Esther Xingwei Lee, Ying Zhao, Felix Chang Tay, Can Chen, Shouhui Dou, Ghayathri Balasundaram, Mohammad Shahbazi, Chee Kian Tham, Wai Hoe Ng, Han Chong Toh, Shu Wang) Stem Cells (2012) 30(5):1021-1029.
  • Targeted Suicide Gene Therapy for Glioma Using Human Embryonic Stem Cell-derived Neural Stem Cells Genetically Modified by Baculoviral Vectors (Ying Zhao, Dang Hoang Lam, Jing Yang, Jiakai Lin, Chee Kian Tham, Wai Hoe Ng, Shu Wang) Gene Therapy (2012) 19(2):189-200.
  • Use of Multimedia Messaging System (MMS) by Junior Doctors for Scan Image Transmission in Neurosurgery. (Ji Min Ling, Kim Zhuan Lim, Wai Hoe Ng) World Neurosurgery (2012) 77(2):384-387. 
  • Telemedicine in Neurosurgery: Breaking Technological & Geographical Barriers (Ji Min Ling, Wai Hoe Ng) Neurosurg Emerg (2011) 16: 120-124.
  • Glioma gene therapy using induced pluripotent stem cell derived neural stem cells. (Lee EX, Lam DH, Wu C, Yang J, Tham CK, Ng WH, Wang S) Mol Pharm (2011) 8(5):1515-1524.
  • Metastatic Pleomorphic Xanthoastrocytoma (PXA) occurring in the scalp: A Case Report (Joel Foo, Wai Hoe Ng) J Clin Neurosci (2011) 18(4): 565-567.
  • FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors (Ivy Ho, Wai Hoe Ng, Paula Lam) Molecular Cancer (2010) 9: 270.
  • Unusual presentations of central nervous system non-Hodgkin and Hodgkin lymphoma: a clinicopathologic review of four tumours from Tan Tock Seng Hospital, Singapore [abstract] (Hwei-Yee Lee, Khoon-Leong Chuah, Siok-Bian Ng, Kheng-Kooi Tan, Wai-Hoe Ng, Ivan Ng, Yih-Yian Sitoh, Lishya Liauw, CC Tchoyoson Lim, Rupak Dutta, Wai-Ming Yap) Brain Pathol (2010) 20 Suppl 1:52.
  • Management of Ventriculo-Peritoneal Shunts in the Paediatric Population (David Low, James M Drake, Wan Tew Seow, Wai Hoe Ng) Asian JNS (2010) 5: 7-14.
  • Augmented Reality Neurosurgical Planning and Navigation for Surgical Excision of Parasagittal, Falcine and Convexity Meningiomas (David Low, Cheng Kiang Lee, Lee Lian Lee, Wai Hoe Ng, Beng Ti Ang, Ivan Ng) Br J Neurosurg (2010) 24(1): 69-74.
  • Revision of vagal nerve stimulation (VNS) electrodes: review and report on use of ultra-sharp monopolar tip (Wai Hoe Ng, Elizabet Donner, Cristina Go, Amal Abou-Hamden, James T Rutka) Child’s Nerv Syst (2010) 26: 1081-1084.
  • Hemispherectomy for the Control of Intractable, Catastrophic Epilepsy in Childhood: Comparison of two surgical techniques in a single institution (Allison Kwan, Wai Hoe Ng, Hiroshi Otsubo, Ayako Ochi, O. Carter Snead III, James T Rutka) Neurosurgery (2010) 67(2 Suppl Operative): 429-436.
  • Image Guidance and Neuromonitoring in Neurosurgery (Wai Hoe Ng, Karim Mukhida, James T Rutka) Child’s Nerv Syst (2010) 26: 491-502.
  • Symptomatic spinal epidural CSF collection after lumbar puncture in a young adult- case report and review of literature (WH Ng, JM Drake)  Child’s Nerv Syst (2010) 26: 259-262.
  • Lateral temporal lobectomy with hippocampal disconnection as an alternate technique for temporal lobe epilepsy (Wai Hoe Ng, Taufik Valiante) J Clin Neurosci (2010) 17:634-635.
  • Stimulation Threshold Potentials of Intra-operative Cortical Motor Mapping using Monopolar Trains of Five in Paediatric Epilepsy Surgery (Wai Hoe Ng, Ayako Ochi, James T Rutka, Hiroshi Otsubo)  Child’s Nerv Syst (2010) 26: 675-679.
  • Telemedicine in Emergency Neurological Service Provision in Singapore- Using technology to overcome limitations (Rajinder Singh, Wai Hoe Ng, Kim En Lee, Ernest Wang, Ivan Ng, Wei Ling Lee) Telemed J E Health (2009) 15(6): 560-565
  • The relationship of parasagittal and falcine meningiomas to the superficial cortical veins: a virtual reality study (Kathleen Joy Khu, Ivan Ng, Wai Hoe Ng) Acta Neurochirurgica (2009) 151(11): 1459-1464.
  • Matrix metalloproteinase 1 is necessary for the migration of human bone marrow derived mesenchymal stem cells towards human glioma (Ivy AW Ho, Kelly YW Chan, Wai H Ng, Chang M Guo, Kam M Hui, Philip Cheang, Paula YP Lam) Stem Cells (2009) 27: 1366–1375.
  • Vanishing glioblastoma after corticosteroid therapy (JJ Goh, SJ See, WH Ng) J Clin Neurosci (2009) 16(9): 1226-1228
  • Intra-op swelling leading to neurological deterioration- argument for moderate size craniotomy (Kathleen Joy Khu, Wai Hoe Ng) J Clin Neurosci (2009) 16(7): 886-888.
  • An unusual parahippocampal lesion presenting with seizures (Wai Hoe Ng, Taufik Valiante) J Clin Neurosci (2009) 16(7): 944.
  • Cryopreservation of Neurospheres derived from Human Glioblastoma Multiforme (Yuk-Kien Chong, Tan-Boon Toh, Norazean Zaiden, Anuradha Poonepalli, Siew-Hong Leong, Catherine E Ong, Yiting Yu, Patrick B Tan, Siew-Ju See, Wai-Hoe Ng, Ivan Ng, Manoor P Hande, Oi-Lian Kon, Beng-Ti Ang, Carol Tang) Stem Cells (2009) 27: 29-39.
  • Aquaporin-4 Expression is increased in edematous meningiomas (Wai Hoe Ng, Jill Wong, Wan Loo Tan, Donald Liew, Tchoyoson Lim, Beng Ti Ang, Ivan Ng) J Clin Neurosci (2009) 16(3): 441-443.
  • Glial Cell-Line Derived Neurotrophic Factor (GDNF) Family of Ligands Confers  Chemoresistance in Ligand-specific fashion in Malignant Gliomas (Wai Hoe Ng, John Wan, Zhun Ni Peng, Heng Phon Too) J Clin Neurosci (2009) 16(3): 427-436. 
  • A teenage girl presenting with thoracic myelopathy.(Wai Hoe Ng, Bin Kee Gan, Wan Tew Seow) J Clin Neurosci (2009) 16(2): 283.
  • Teleradiology and Emergency Neurosurgery- Presence in a small Asian city state and need in a large Canadian Province (Wai Hoe Ng, Ernest Wang, Ivan Ng, Mark Bernstein) Journal of Brain Disease (2009): 1: 7-11.
  • Diffusion Tensor Tractography: Corticospinal Tract Fiber Reduction is Associated with Temporary Hemiparesis in Benign Extra-Cerebral (Wai Hoe Ng, Dennis Cheong, Kathleen Joy Khu, Govindasamy Venkatesh, Tchoyoson Lim) Neurosurgery (2008) 63(3): 452-458.
  • Diffusion-weighted MR imaging: diagnosing atypical or malignant meningiomas and detecting tumor dedifferentiation (Nagar VA, Ye J, Ng WH, Chan YH, Hui F, CK Lee, Lim CCT) Am J Neuroradiol (2008) 29(6): 1147-1152.
  • Parieto-occipital ventricular catheter insertion. Validation of entry point and trajectory landmarks using 3-D imaging technology.(Cheng Kiang Lee, Lee Lian Tay, Wai Hoe Ng, Ivan Ng, Beng Ti Ang) Surgical Neurology (2008) 70(3): 274-277.
  • Characterization of  Numb expression in astrocytomas (Benedict Yan, Feroz Mohd Omar, Kakoli Das, Wai Hoe Ng, Chinghway Lim, Koh Shiuan, Celestial T Yap, Manuel Salto-Tellez) Neuropathology (2008) 28: 479-484.
  • Targeting regions with highest lipid content on MR Spectroscopy may improve diagnostic yield in stereotactic biopsy (Wai Hoe Ng, Tchoyoson Lim) J Clin Neurosci (2008) 15(5): 502-506.
  • Elderly pleomorphic xanthoastrocytoma (PXA) may portend a poorer prognosis. (Wai Hoe Ng, Tchoyoson Lim, Tseng Tsai Yeo) J Clin Neurosci (2008) 15(4): 476-478. 
  • A simple and cost-effective method of fixation of deep brain stimulation (DBS) electrode. (Wai Hoe Ng, John Thomas) Acta Neurochir (2008) 150: 387–389.
  • Central Neurocytoma: Typical Magnetic Resonance Imaging and Atypical Ventricular    Dissemination (Ing Berne Yeh, Maosheng Xu, Wai Hoe Ng, Jieru Ye, Daiwen Yang, CC Tchoyoson Lim) Magn Reson Imaging (2008) 26(1): 59-64.
  • Ex-vivo NMR of unprocessed tissue in water: a simplified procedure for studying intracranial neoplasms (Xu M, Ye J, Yang D, Xu X, Yeo TT, Ng WH, Lim CC) Anal Bioanal Chem. (2007) 389(7-8): 2153-2159.
  • Neurosurgical strategies to maximize glioma resection with minimal morbidity (Wai Hoe Ng, Kathleen Joy Khu) Asian JNS (2007) 1: 9-15.
  • Neuro-oncology at the crossroads- Editorial (WH Ng, SJ See) Ann Acad Med Singapore  (2007) 36: Editorial.
  • Multivoxel MR spectroscopic imaging- distinguishing intracranial tumours from non-neoplastic disease (VA Nagar, JR Ye, MS Xu, WH Ng. TT Yeo, PL Ong, CCT Lim) Ann Acad Med Singapore (2007) 36: 309-313.
  • The Role of Surgery in High Grade Glioma - is surgical resection justified?  A Review of the current knowledge (Boon Chuan Pang, Wei-Hwang Wan, Cheng Kiang Lee, Kate Khu, Wai Hoe Ng) Ann Acad Med Singapore (2007) 36: 358-363.
  • Improvements in Quality of Care Resulting from a Formal Multidisciplinary Tumour Clinic in the Management of High Grade Glioma (Michael F Back, Emily Ang Liling, Ng Wai Hoe, See Siew Ju, Lim CC Tchoyoson, Tay Lee Lee, Yeo Tseng Tsai) Ann Acad Med Singapore (2007) 36: 347-351.
  • Awake Craniotomy under local anaesthesia and monitored conscious sedation for resection of brain tumours in eloquent cortex – Outcomes in 20 patients (David Low, Ivan Ng, Wai Hoe Ng) Ann Acad Med Singapore (2007) 36: 326-331.
  • Improved Median Survival for Glioblastoma Multiforme Following Introduction of Adjuvant Temozolamide Chemotherapy. (Michael F Back, Emily Ang Liling, Ng Wai Hoe, See Siew Ju, Lim CC Tchoyoson, Chan SP, Yeo Tseng Tsai) Ann Acad Med Singapore (2007) 36: 338-342.
  • Multimedia Messaging Service (MMS) teleradiology in the provision of emergency neurosurgery services (Wai Hoe Ng, Ernest Wang, Ivan Ng) Surg Neurol. (2007) 67(4):338-341.
  • Chromosome 1p and 19q deletions identify rare dysembryoplastic neuroepithelial tumours that may evolve into oligodendroglioma or oligoastrocytoma.  (Michael Gonzales, Susan Dale, Marleen Susman, Prudence Nolan, Wai Hoe Ng, Wirginia Maixner, John Laidlaw, David Ashley) Neuropathology (2007) 27, 324-330.
  • Higher glioblastoma tumour burden confers resistance to chemotherapeutic agent- in vitro evidence. (Wai Hoe Ng, Guo Qiang Wan, Heng Phon Too) J Clin Neurosci (2007) 14(3), 261-266.
  • Disseminated spread of a case of recurrent oligodendroglioma (WHO Grade II) (Wai Hoe Ng, Tchoyoson Lim, Kheng Kooi Tan) J Clin Neurosci (2006) 13(5), 602-607.
  • Apoptosis and Traumatic Brain Injury- A primer for clinicians (Jill Wong, Wai Hoe Ng, Feng Zhi Wei, Ivan Ng) Neurocritical Care (2005) 3(2):177-182.
  • Comparison of Magnetic Resonance Spectroscopy and Perfusion Weighted Imaging in Pre-surgical Grading of Oligodendroglial Tumors ( Maosheng Xu, Siew Ju See, Wai Hoe Ng, Earnest Arul, Michael F Back, Tseng Tsai Yeo, CC Tchoyoson Lim) Neurosurgery (2005) 56(5):919-926.
  • Spinal and extracranial metastatic dissemination in malignant gliomas- review (Wai Hoe Ng, Tseng Tsai Yeo, Andrew H Kaye) J Clin Neurosci (2005) 12(4), 379-382.
  • A Case of Hyperdense Diploic Epidermoid Cyst on CT Scan Mimicking Meningioma (Wai Hoe Ng, Peter Mitchell, Lara Tickell, Andrew Kaye) J Clin Neurosci (2004) 11(8), 930-931.
  • Non-traumatic spontaneous acute epidural haematoma- report of two cases and review of the literature (Wai Hoe Ng, Tseng Tsai Yeo, Wan Tew Seow) J Clin Neurosci (2004) 11(7), 791-794.
  • Co-Existence of Aneurysmal Subarachnoid Haemorrhage and Pituitary Apoplexy: Case Report and Review of the Literature (John Laidlaw, Brian Tress, Michael Gonzales, Alison Wray, Wai Hoe Ng, Jennifer O’Brien) J Clin Neurosci (2003) 10(4), 478-482. 
  • Lymphocytic Hypophysitis- Review (Wai Hoe Ng, Michael Gonzales, Andrew Kaye) J Clin Neurosci (2003) 10(4), 409-413.
  • Lymphocytic Hypophysitis Mimicking Pituitary Adenoma (Anita Skandarajah, Wai Hoe Ng, Michael Gonzales, Andrew Kaye) J Clin Neurosci (2002) 9(5), 586-589.
  • Spinal Epidural Haematoma: MRI aided diagnosis (Wai Hoe Ng, Tchoyoson Lim, Kheng Kooi Tan) J Clin Neurosci (2002) 9(1), 92-946.
  • Nitric Oxide and Subarachnoid Hemorrhage: Elevated Levels in Cerebrospinal Fluid and Their Implications (Wai Hoe Ng, Shabbir Moochhala, Tseng Tsai Yeo, Peck Leong Ong, Puay Yong Ng) Neurosurgery (2001) 49:622-627.
  • Tethered Cord Syndrome Preceding Syrinx Formation- Serial Radiological Documentation (Wai Hoe Ng, Wan Tew Seow) Child’s Nerv Syst (2001) 17:494-496.
  • Intracranial Cerebral Aneurysm Secondary To Hyperdynamic Circulation Treated By Bilateral Carotid Artery To Proximal Middle Cerebral Artery Bypass-A Case Report (Wai Hoe Ng, Ning Chou, Timothy Lee) J Clin Neurosci (2001) 8(6), 580-583.
  • Desmoid Tumor (Fibromatosis) of the Breast: A Clinician’s Dilemma- A Case Report & Review of Literature (Ng WH, Lee JSY, Poh WT, Wong CY) Arch Surg. (1997) 132: 444-446.   

Research Trials

  • Principle Investigator: NMRC-NIG: Investigating role of electrical subthalamic and pallidal stimulation of the brain on the expression of GDNF family of ligands and GFRα receptor splice isoform and neurogenesis.
  • Principle Investigator: Agency for Science, Technology & Research Science & Engineering Research Council Neurodevice Inter-RI Programme: Wireless Fully-Implantable Neuroprobe Microsystem for Motor Prosthesis & Neuroscience. Project IX: Nonhuman Primate Experiments.
  • Principle Investigator: Agency for Science, Technology & Research Science & Engineering Research Council Neurodevice Inter-RI Programme: Wireless Fully-Implantable Neuroprobe Microsystem for Motor Prosthesis & Neuroscience Phase 2.