Shi-Yan Ng, Ph.D
Visiting Scientist, National Neuroscience InstituteJunior Investigator, Institute of Molecular and Cell Biology
Institute of Molecular and Cell Biology61 Biopolis Drive, 5-07Proteos, Singapore 138673Tel: 6586 9525Website: http://www.imcb.a-star.edu.sg/php/iji-syn.php
Overview of Laboratory
Our research program focuses on the biology of neurodegeneration. We are broadly interested in using human induced pluripotent stem cells to model neurodegenerative diseases such as Parkinson’s disease, Amyotrophic Lateral Sclerosis and dementia. Combining genomic technologies with drug screening and high content imaging, we aim to uncover mechanisms underlying specific neuronal vulnerability and how this knowledge can be used to prevent or treat human neurodegeneration.
We believe in collaborating with academic, industry and clinician partners to advance scientific knowledge. Some of our collaborators include Lee Rubin (Harvard Stem Cell Institute), Syros Pharmaceuticals (Cambridge, MA), National Neuroscience Institute, National University of Singapore and the Genome Institute of Singapore.
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