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Hydroquinone - Side Effects, Precautions, and Contraindications

What side effects can Hydroquinone cause?

Certain side effects of Hydroquinone are common and may even disappear during treatment. If any of the following side effects on the sites of application do not go away or are severe, please consult your doctor:

  • Itching
  • Dryness
  • Peeling
  • Mild burning
  • Redness
  • Stinging sensation

If you experience any of the following side effects on the sites of application, please consult your doctor immediately:

  • Acne
  • Blisters
  • Crusting on skin
  • Oozing from skin
  • Scaling skin
  • Severe burning sensation
  • Severe dryness
  • Severe irritation or itching
  • Stretch marks
  • Swelling
  • Tiny red lines or blood vessels showing through the skin (telangiectasia)
  • Unusual skin coloration

Before taking Hydroquinone, what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication or have sulfite allergy
  • You are pregnant, planning to become pregnant, or breastfeeding
  • You have asthma or any other skin conditions (e.g. eczema, psoriasis)
  • You are on ultraviolet light therapy, sun lamps or tanning bed.
    • Avoid prolonged exposure to sunlight or ultraviolet light to prevent re-pigmentation from occurring. Use a broad-spectrum sunscreen product with Sun Protection Factor (SPF) of at least 30 and wear protective clothing when you are exposed to direct sunlight.

Prolonged use of hydroquinone has been associated with the development of exogenous ochronosis (a persistent blue-black pigmentation). Therefore, please use as instructed by your doctor and stop after you have achieved the desired lightening effect.

What food or medicine must I avoid when I take Hydroquinone?

Hydroquinone - Additional Information

​The symptoms of a drug allergy include one or more of the following:

● Swollen face/eyes/lips/tongue

● Difficulty in breathing

● Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

  • Updated on
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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